裙带菜可溶性膳食纤维对小鼠血管生成素样蛋白3蛋白表达的影响
摘 要 目的:研究裙带菜可溶性膳食纤维对小鼠血管生成素样蛋白3蛋白表达的影响。方法: 40只小鼠分为4组(n=10): 对照组(C57BL/6J小鼠);高脂模型组(载脂蛋白E缺陷小鼠),膳食纤维低剂量组(5%),膳食纤维高剂量组(10%);经裙带菜可溶性膳食纤维处理8周后,用Western blotting检测血管生成素样蛋白3(Angptl 3)蛋白表达水平。结果: 裙带菜可溶性膳食纤维上调Angptl3蛋白表达水平。结论:裙带菜可溶性膳食纤维能下调小鼠血管生成素样蛋白3蛋白表达。
关键词:裙带菜;可溶性膳食纤维;血管生成素样蛋白3;载脂蛋白E缺陷小鼠
THE EFFECT OF UNDARIA PINNATIFIDA DIETARY FIBER ON THE EXPRESSION OF ANGPTL3 IN MICE
Abstract: Objective:Objective: To study Undaria soluble dietary fiber on mouse angiopoietin-like 3 protein (Angptl 3) expression. Methods: 40 mice were divided into 4 groups (n = 10): control group (C57BL/6J mice); model group (apolipoprotein E-deficient mice), dietary fiber low-dose group (5%) dietary fiber, high-dose group (10%); After treatment for 8 weeks, Angptl 3 protein expression was determined by Western blotting. Results: Undaria pinnatifida soluble dietary fiber decreases the protein expression of Angptl3. Conclusion: Undaria pinnatifida soluble dietary fiber can lower the protein expression of Angptl 3 in mice. [来源:http://www.doc163.com]
Key words: Undaria pinnatifida; Soluble dietary fiber; angiopoietin-like protein 3; apolipoprotein E deficient mice
目 录 4100字
摘 要 1
关键词 1
1 前言 2
2 材 料 与 方 法 2
2.1 待检样本及试剂 2
2.2 实验动物及分组 2
2.3 Angptl 3蛋白表达的Western blotting分析 2
2.4 统计分析 3
3 结 果 3
4 讨 论 4
参考文献 5
致 谢 7 [资料来源:http://doc163.com]